Thermo Fisher Scientific EID1 Polyclonal Antibody
EID1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 Immunocytochemistry에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol 버퍼에 보관되며, 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human EID1 (amino acids 86–106, UniProt ID: Q9Y6B2-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635354 |
Product Specific Information
This antibody detects endogenous levels of total EID1 protein.
Target Information
E1A-like inhibitor of differentiation-1 (EID-1) is an acetyltransferase enzyme that binds to the retinoblastoma protein (Rb) and the adenovirus E1A-associated cellular p300 transcriptional co-activator. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. It acetylates both histones and non-histone proteins such as the NCOA3 co-activator, tagging histones for transcriptional activation. EID-1 also interacts with phosphorylated CREB protein, mediating cAMP gene regulation and acting as a co-activator for transcription of cAMP-responsive genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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