Thermo Fisher Scientific PPP1R10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PPP1R10. Recombinant protein control fragment (Product #RP-103267). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PPP1R10,uniProtId:Q96QC0-1,ncbiNodeId:9606,antigenRange:364-462,antigenLength:940,antigenImageFileName:PA5-63345_PPP1R10_Q96QC0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63345_PPP1R10_Q96QC0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645849

Product Specific Information

Immunogen sequence: LMDTASLEPG ALDAKPVESP GDPNQLTRKG RKRKSVTWPE EGKLREYFYF ELDETERVNV NKIKDFGEAA KREILSDRHA FETARRLSHD NMEEKVPWV

Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 97%.

Target Information

RNA polymerases transcribe nuclear genes for ribosomal RNA, thus representing ribosomal biogenesis. RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA. Different subunits of the Pol I transcription machinery are targets of various physiological stimuli, which suggests that multiple signaling pathways are involved in carrying out Pol I transcription. RPA40 and RPA16 are subunits of Pol I that associate with each other at an early stage of RNA polymerase I assembly. RPA40 is essential for the function and integrity of the complex and is also an essential subunit of RNA polymerase III (Pol III). RPA40, RPA16 and RPA135 encode the three subunits of RNA polymerase I, respectively. RPA194 is the largest subunit of RNA Pol I and is not a component of Pol II and Pol III.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.