Thermo Fisher Scientific PPP1R10 Polyclonal Antibody
Human PPP1R10 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 완충액에 보관. 연구용 전용 제품으로 높은 특이성과 재현성 제공.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PPP1R10. Recombinant protein control fragment (Product # RP-103267) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C; avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645849 |
Product Specific Information
Immunogen sequence:
LMDTASLEPG ALDAKPVESP GDPNQLTRKG RKRKSVTWPE EGKLREYFYF ELDETERVNV NKIKDFGEAA KREILSDRHA FETARRLSHD NMEEKVPWV
Antigen sequence identity:
- Mouse: 96%
- Rat: 97%
Target Information
RNA polymerases transcribe nuclear genes for ribosomal RNA, representing ribosomal biogenesis. RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes coding for large ribosomal RNA.
Different subunits of the Pol I transcription machinery respond to various physiological stimuli, indicating multiple signaling pathways are involved in Pol I transcription.
RPA40 and RPA16 are subunits of Pol I that associate early in RNA polymerase I assembly. RPA40 is essential for complex integrity and is also a subunit of RNA polymerase III (Pol III).
RPA40, RPA16, and RPA135 encode subunits of RNA polymerase I, while RPA194 is the largest subunit of RNA Pol I and not part of Pol II or Pol III.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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