Thermo Fisher Scientific SUZ12 Polyclonal Antibody
Thermo Fisher Scientific의 SUZ12 Polyclonal Antibody는 인간 SUZ12 단백질을 인식하는 토끼 IgG 항체로, WB 및 IHC(P) 실험에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 연구용으로 안정적인 신호 검출에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | SUZ12 antibody was raised against a 19 amino acid peptide near the center of human SUZ12. The immunogen is located within amino acids 400–450 of SUZ12. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890356 |
Product Specific Information
Positive controls that may be used include:
- Human Liver Tissue Lysate
- Human Lung Tissue Slide
Target Information
SUZ12 (polycomb protein SUZ12) is a zinc finger gene identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1.
SUZ12 is also a component of the PRC2/EED-EZH2 complex, which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The encoded protein contains a zinc finger domain in the C terminus of the coding region.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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