Thermo Fisher Scientific Notch1 Monoclonal Antibody (OTI4C9), TrueMAB
인간 Notch1 단백질을 인식하는 마우스 단일클론 항체로 Western blot 및 파라핀 IHC에 적합합니다. 고순도 친화크로마토그래피 정제, PBS/BSA/glycerol 완충액에 보관되며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C9 |
| Immunogen | Recombinant protein expressed in E. coli corresponding to amino acids 2300–2556 of human NOTCH1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Notch gene family encodes transmembrane proteins with multiple cysteine-rich EGF-like repeats in the extracellular region. Four Notch genes (Notch1, Notch2, Notch3, and Notch4/Int-3) have been described in mammals and are involved in differentiation of the nervous system and other tissues.
EGF-like proteins Delta and Serrate serve as ligands for Notch1. Mature Notch proteins are heterodimeric receptors formed by cleavage of Notch pre-proteins into an extracellular subunit (NEC) and a transmembrane subunit (Ntm) containing the intracellular region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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