Thermo Fisher Scientific AKR1C4 Polyclonal Antibody
AKR1C4 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 고순도의 액상 형태로 제공됩니다. 인간 시료에 반응하며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–4 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DPKYQRVELNDGH) corresponding to the N-terminus amino acids of AKR1C4 (aa 2–15) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10984032 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
Target Information
This gene encodes a member of the aldo/keto reductase superfamily, which includes more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. They exhibit overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in the liver. The gene shares high sequence identity with three other family members and is clustered with them at chromosome 10p15–p14.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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