Thermo Fisher Scientific ETFA Monoclonal Antibody (2F8A5)
ETFA 단백질을 표적으로 하는 Thermo Fisher Scientific의 마우스 단클론 항체(2F8A5). Western blot, IHC, ICC, Flow, ELISA 등 다양한 응용 가능. 고순도 Protein G 정제, 1 mg/mL 농도, PBS buffer 및 sodium azide 포함. 연구용으로만 사용.
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Thermo Fisher Scientific ETFA Monoclonal Antibody (2F8A5)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F8A5 |
| Immunogen | Purified recombinant fragment of human ETFA (AA: 134–333) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091269 |
Target Information
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase.
Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria, in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids.
Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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