Thermo Fisher Scientific HEC1 Recombinant Rabbit Monoclonal Antibody (ARC0741)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC0741

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 543-642 of human HEC1/NDC80 (O14777) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HEC1,uniProtId:O14777-1,ncbiNodeId:9606,antigenRange:543-642,antigenLength:642,antigenImageFileName:MA5-35354_HEC1_O14777-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35354_HEC1_O14777-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.16 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849255

Product Specific Information

Immunogen sequence: ESTVNQGLSE AMNELDAVQR EYQLVVQTTT EERRKVGNNL QRLLEMVATH VGSVEKHLEE QIAKVDREYE ECMSEDLSEN IKEIRDKYEK KATLIKSSEE

Target Information

Hec1 is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.