Thermo Fisher Scientific N-WASP Recombinant Rabbit Monoclonal Antibody (ARC0737)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC0737

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 350-450 of human N-WASP/WASL (O00401) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:N-WASP,uniProtId:O00401-1,ncbiNodeId:9606,antigenRange:350-450,antigenLength:505,antigenImageFileName:MA5-35352_N-WASP_O00401-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35352_N-WASP_O00401-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.8 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849253

Product Specific Information

Immunogen sequence: LPSSAPSGPP PPPPSVLGVG PVAPPPPPPP PPPPGPPPPP GLPSDGDHQV PTTAGNKAAL LDQIREGAQL KKVEQNSRPV SCSGRDALLD QIRQGIQLKS V

Target Information

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.