Thermo Fisher Scientific ERAL1 Polyclonal Antibody
Thermo Fisher Scientific의 ERAL1 Polyclonal Antibody는 인간 ERAL1 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot과 ELISA에 적합합니다. 미토콘드리아 내막 및 기질 단백질 검출에 사용되며, 고순도 친화 크로마토그래피 정제 제품입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 198–437 of human ERAL1 (NP_005693.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.04 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804460 |
Product Specific Information
Immunogen sequence:
DLVVVLVDVS DKWTRNQLSP QLLRCLTKYS QIPSVLVMNK VDCLKQKSVL LELTAALTEG VVNGKKLKMR QAFHSHPGTH CPSPAVKDPN TQSVGNPQRI GWPHFKEIFM LSALSQEDVK TLKQYLLTQA QPGPWEYHSA VLTSQTPEEI CANIIREKLL EHLPQEVPYN VQQKTAVWEE GPGGELVIQQ KLLVPKESYV KLLIGPKGHV ISQIAQEAGH DLMDIFLCDV DIRLSVKLLK
Positive Samples: SKOV3, HeLa, U-87MG, NCI-H460, Mouse kidney, Mouse heart, Rat liver
Cellular Location: Mitochondrion inner membrane, Mitochondrion matrix, Peripheral membrane protein
Target Information
ERAL1 encodes a GTPase localized to the mitochondrion. It binds to the 3′ terminal stem loop of 12S mitochondrial rRNA and is essential for the assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene can cause mitochondrial dysfunction, growth retardation, and apoptosis. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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