Thermo Fisher Scientific Bovine Lactoferrin Polyclonal Antibody, Biotin
소, 양에서 반응하는 Biotin 결합 폴리클로날 항체로 Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. 정제된 소 락토페린 단백질을 면역원으로 제작되었으며, 친화 크로마토그래피로 정제됨. -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Sheep |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Purified Bovine Lactoferrin protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Lactoferrin (LF) is an iron-binding glycoprotein consisting of a single polypeptide chain (~80 kDa) folded into two homologous lobes, each capable of reversibly binding one ferric ion (Fe³⁺). It is found in external fluids such as milk and mucosal secretions and is a major component of secondary granules in neutrophils.
Lactoferrin exhibits various biological functions including:
- Regulation of iron homeostasis
- Host defense against microbial infections
- Anti-inflammatory activity
- Regulation of cellular growth and differentiation
- Protection against cancer development and metastasis
Three isoforms (LTF-α, LTF-β, LTF-γ) have been identified. Receptors for LTF are expressed in the gastrointestinal tract, macrophages, lymphocytes, neutrophils, platelets, and some bacteria.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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