Thermo Fisher Scientific GNPNAT1 Polyclonal Antibody
GNPNAT1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, ICC/IF, ELISA에 적합하며 인간, 마우스, 랫트 시료에 반응. 액상 형태로 제공되며 -20°C에서 보관. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–91 of human GNPNAT1 (NP_932332.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.72 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914150 |
Product Specific Information
- Positive test controls: HT-29, LO2, BxPC-3, mouse kidney, mouse lung, rat liver, rat kidney
- Immunogen sequence:
MKPDETPMFD PSLLKEVDWS QNTATFSPAI SPTHPGEGLV LRPLCTADLN RGFFKVLGQL TETGVVSPEQ FMKSFEHMKK SGDYYVTVVE D
Target Information
Glucosamine-6-phosphate-N-acetyl Transferase (GNPNAT1) is a key enzyme in the hexosamine biosynthetic pathway. It converts D-glucosamine 6-phosphate to N-acetyl-D-glucosamine 6-phosphate, the acetylation step allowing carbon and nitrogen to enter into the hexosamine biosynthetic pathway. Inhibition of GNPNAT1 has been reported to promote proliferation and aggressiveness of castration-resistant prostate cancer (PMID: 27194471).
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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