Thermo Fisher Scientific PPP1R7 Polyclonal Antibody
PPP1R7 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 파라핀 포매 조직 면역조직화학(IHC-P)에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용 전용 시약.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PPP1R7. Recombinant protein control fragment (Product #RP-96028). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645879 |
Product Specific Information
Immunogen sequence:
EEHELPVDME TINLDRDAED VDLNHYRIGK IEGFEVLKKV KTLCLRQNLI KCIENLEELQ SLRELDLYDN QIKKIENL
Antigen sequence identity:
- Mouse: 95%
- Rat: 36%
Target Information
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential mechanism regulating cellular functions such as division, homeostasis, and apoptosis. Protein phosphatase 1 (PP1) holoenzyme is typically a trimeric complex composed of regulatory, variable, and catalytic subunits.
Sds22, also known as PPP1R7 (protein phosphatase 1 regulatory subunit 7), is a 360 amino acid nuclear protein containing ten LRR (leucine-rich repeat) domains. It acts as a regulatory subunit of the PP1 complex and is expressed in various tissues, suggesting a role in protein regulation throughout the cell. Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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