Thermo Fisher Scientific PPP1R7 Polyclonal Antibody
PPP1R7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC 등 다양한 응용에 적합. 인간 시료 반응성, 고순도 항원 친화 크로마토그래피 정제, 안정적 액상 형태로 장기 보관 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PPP1R7. Recombinant protein control fragment (Product #RP-102621). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645878 |
Product Specific Information
Immunogen sequence:
LENNNKLTML DIASNRIKKI ENISHLTELQ EFWMNDNLLE SWSDLDELKG ARSLETVYLE RNPLQKDPQY RRKVMLALPS VRQIDATF
Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 100%
Target Information
In eukaryotes, phosphorylation and dephosphorylation of proteins on serine and threonine residues regulate a wide range of cellular functions such as division, homeostasis, and apoptosis. Protein phosphatase 1 (PP1) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit.
Sds22, also known as PPP1R7, is a 360-amino-acid nuclear protein containing ten LRR (leucine-rich) repeats. It functions as a regulatory subunit of the PP1 complex and is expressed in various tissues, suggesting a role in protein regulation throughout the cell. Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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