Thermo Fisher Scientific OCT4 Monoclonal Antibody (OTI2B6), TrueMAB
인간 OCT4(POU5F1)를 인식하는 마우스 단클론 항체로, Western blot에 적합합니다. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도의 액상 형태로 제공됩니다. 줄기세포 연구 및 유도만능줄기세포(iPS) 관련 연구에 활용 가능합니다.
- 카탈로그번호
- TA506797
- 판매단위
- pk
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Applications and Tested Dilution
- Western Blot (WB): 1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B6 |
| Immunogen | Full length human recombinant protein of human POU5F1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
POU5F1, also known as Oct-4, is a maternally expressed octamer-binding transcription factor essential for early embryonic development. Its role in maintaining pluripotency has made it a key factor in stem cell and induced pluripotent stem (iPS) cell research. Expression of POU5F1, along with Sox2, Klf4, Lin28, and c-Myc, enables reprogramming of somatic cells into iPS cells. Recent advancements have shown that non-viral expression plasmids can be used to generate iPS cells, improving safety for regenerative medicine applications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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