Thermo Fisher Scientific TIAF1 Polyclonal Antibody
Rabbit polyclonal antibody specific for human TIAF1 단백질 검출용. IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 시약. 4°C 단기 보관, 장기 보관은 -20°C 권장. 연구용 전용 제품.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TIAF1 Polyclonal Antibody
Applications
Tested Application and Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TIAF1. Recombinant protein control fragment (Product # RP-100356) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648457 |
Product Specific Information
Immunogen sequence:
MSSPSSPFRE QSFLCAAGDA GEESRVQVLK NEVRRGSPVL LGWVEQAYAD KCV- Highest antigen sequence identity to the following orthologs:
- Mouse: 30%
- Rat: 28%
Target Information
TIAF-1 (TGFB1-induced anti-apoptotic factor 1), also known as MYO18A, is a TGFB1-induced anti-apoptotic factor that inhibits the cytotoxic effects of TNF-alpha, TRADD, and FADD.
It localizes to the nucleus and is significantly upregulated in activated helper T lymphocytes (TH2) during chronic kidney and liver allograft rejection.
Suppression of TIAF1 expression by siRNA prevents UV irradiation-mediated p53 phosphorylation and nuclear translocation.
TIAF1 is essential in the p53- and WOX1-mediated cell death and plays a role in aggregation-dependent control of tumor progression, metastasis, and regulation of cell death.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.