Thermo Fisher Scientific Phl p 1 Chimeric Recombinant Human Monoclonal Antibody (Clone 25)

Applications and Tested Dilution

Product Specifications

Product Specific Information

This antibody binds to the Timothy grass allergen Phl p 1 and shows cross-reactivity with natural group 1 allergens from a variety of grass species such as oat, sweet vernal grass, Bermuda grass, rye grass, common reed, Kentucky blue grass, rye, wheat, and maize (weak).

Target Information

Phl p 1 binds to specific receptors on the surface of immune cells, including TLR4 (Toll-like receptor 4) and MD-2 (myeloid differentiation factor 2).
This interaction triggers a signaling cascade that activates immune cells and releases inflammatory mediators, leading to allergic symptoms.
The Phl p 1–TLR4–MD-2 interaction is a key mechanism in grass pollen allergy development and provides insights for potential therapeutic strategies against allergic reactions.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.