Thermo Fisher Scientific APOB48R Polyclonal Antibody
Human APOB48R 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 1 mg/mL 농도의 액상 형태입니다. PBS/glycerol buffer에 보관하며, -20°C에서 안정적으로 저장 가능합니다.
- 카탈로그번호
- PA599847
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human APOBR (Accession Q0VD83), corresponding to amino acid residues P1033–G1083 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2818780 |
Product Specific Information
This antibody detects endogenous levels of total APOB48R.
Target Information
APOB48R is a macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to similar domains in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). It internalizes TRL outside the macrophage context and may supply essential lipids to reticuloendothelial cells. It may also contribute to foam cell formation under elevated TRL and remnant lipoprotein (RLP) conditions. APOB48R mediates rapid, high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized VLDL devoid of APOE in vitro in macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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