Thermo Fisher Scientific Human SIPA1L3 Synthetic Peptide
인간 SIPA1L3 단백질의 아미노 말단 19개 아미노산 서열을 기반으로 한 합성 펩타이드입니다. 항체 PA5-20849와 함께 차단 펩타이드로 사용 가능하며, 정제된 액상 형태로 제공됩니다. PBS(pH 7.2, 0.1% BSA) 용액에 보관하며, 연구용으로만 사용됩니다.
- 카탈로그번호
- PEP0963
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human SIPA1L3 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the amino terminus of human SIPA1L3.
PEP-0963 can be used as a blocking peptide with polyclonal antibody PA5-20849.
Target Information
Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that it may function to balance Rap1 by counteracting RapGEFs.
Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation.
Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays additional roles in development and cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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