
Thermo Fisher Scientific Human PLEKHM3 Synthetic Peptide
인간 PLEKHM3 단백질의 C-말단 13개 아미노산 서열에 해당하는 합성 펩타이드입니다. 폴리클로날 항체 PA5-20851의 블로킹 펩타이드로 사용 가능합니다. 정제된 액상 형태로 제공되며 PBS/BSA 버퍼에 보관됩니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PEP0965
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human PLEKHM3 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids near the carboxy terminus of human PLEKHM3.
PEP-0965 can be used as a blocking peptide with polyclonal antibody PA5-20851.
Target Information
PLEKHM3, also known as DAPR, is a member of the M family of Pleckstrin homology domain-containing proteins.
PLEKHM3 was initially identified through chromatin immunoprecipitation and CpG microarray analysis examining proteins regulated by myocyte-enhancing factor 2.
In C2C12 myoblast cells, PLEKHM3 binds to the PI3K signaling member protein kinase B in the cytosol prior to differentiation into myotubes.
Following the initiation of differentiation, PLEKHM3 was also found in membrane fractions.
Knockdown of PLEKHM3 expression by RNAi resulted in inhibition of myotube formation, suggesting that PLEKHM3 is a key component required by myoblasts for orchestrating their differentiation during myogenesis.
Usage Note
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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