Thermo Fisher Scientific Syntenin 1 Polyclonal Antibody
Human 및 Zebrafish에 반응하는 Rabbit Polyclonal 항체로, Western blot과 IHC에 적합합니다. SDCBP 중간 영역에 대한 합성 펩타이드로부터 유래했으며, Protein A로 정제된 액상 형태입니다. 세포골격 및 신호전달 연구용으로 사용됩니다.
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- PA542592
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- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1.25 µg/mL | - |
| Immunohistochemistry (IHC) | 5 µg/mL | - |
| Dot blot (DB) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human SDCBP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2610505 |
Product Specific Information
Peptide sequence:
VGIRRAEIKQ GIREVILCKD QDGKIGLRLK SIDNGIFVQL VQANSPASLV
Sequence homology:
Cow: 100%
Dog: 100%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 92%
Target Information
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of various transmembrane proteins. This protein may affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and transcription factor activation. It is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found in the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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