Thermo Fisher Scientific GPNMB Polyclonal Antibody
GPNMB 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 사용 가능하며, Human 종에 반응. 합성 펩타이드 면역원 기반, 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human GPNMB (aa 74–123) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607808 |
Product Specific Information
- Peptide sequence: KGGRVQAVLT SDSPALVGSN ITFAVNLIFP RCQKEDANGN IVYEKNCRNE
- Sequence homology:
Cow: 93%
Dog: 79%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 85%
Rat: 100%
Zebrafish: 77%
Target Information
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein.
GPNMB shows expression in lowly metastatic human melanoma cell lines and xenografts but not in highly metastatic cell lines.
It may be involved in growth delay and reduction of metastatic potential.
Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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