Thermo Fisher Scientific GAK Polyclonal Antibody
GAK 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P) 검증 완료. Human과 Mouse에 반응하며 Rat에서도 예측 반응. KLH 접합 합성 펩타이드로 면역화. 단백질 A 및 항원 친화 크로마토그래피로 정제된 고순도 항체.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 1140–1170 amino acids from the C-terminal region of human GAK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10987345 |
Product Specific Information
This antibody is predicted to react with rat based on sequence homology.
Target Information
GAK (Cyclin-G-associated kinase) is a serine/threonine kinase originally identified as a cyclin G-associated protein. It does not activate CDK5 nor is it activated by cyclin G. GAK functions as an auxilin homolog involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression slightly oscillates during the cell cycle, peaking at G1.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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