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ELK Biotechnology MEK-1/2 rabbit pAb
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MEK-1/2 단백질을 인식하는 토끼 다클론 항체로, IF, WB, IHC, ELISA에 사용 가능. 인간 유래 합성 펩타이드로 면역화됨. 세포 내 MAPK 신호전달 경로 연구에 적합. -20°C에서 1년 보관 가능.
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ELK Biotechnology ES2772-100UL MEK-1/2 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES2772-50UL MEK-1/2 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology MEK-1/2 rabbit pAb
ELK Biotechnology MEK-1/2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | MEK-1/2 rabbit pAb |
| Alternative Names | MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein kinase 2 |
| Applications | IF; WB; IHC; ELISA |
| Recommended Dilutions | IF: 1:50–200; WB: 1:500–2000; ELISA: 1:10000–20000; IHC: 1:50–300 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MEK1/2 (AA range: 189–238). |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 43 kD |
| Gene ID (Human) | 5604 / 5605 |
| Human Swiss-Prot No. | Q02750 / P36507 |
| Cellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Also found in nucleus and membrane (peripheral membrane protein). Localizes at centrosomes during prometaphase, midzone during anaphase, and midbody during telophase/cytokinesis (PubMed:14737111). Membrane localization may be regulated by interaction with KSR1 (PubMed:10409742). |
| Species Reactivity | Human; Mouse; Rat; Monkey |
Background
The protein encoded by this gene belongs to the dual specificity protein kinase family and functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), integrate multiple biochemical signals. This kinase lies upstream of MAP kinases and activates them upon various extra- and intracellular stimuli. As a key component of the MAP kinase signal transduction pathway, it is involved in cellular processes such as proliferation, differentiation, transcription regulation, and development.
[Provided by RefSeq, Jul 2008]
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