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ELK Biotechnology MARK2 rabbit pAb
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MARK2 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IF, ELISA에 적합합니다. 세포 극성과 미세소관 안정성 연구에 활용되며, Human, Mouse, Rat, Monkey 시료에 반응합니다. -20℃에서 1년 보관 가능합니다.
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ELK Biotechnology ES2747-100UL MARK2 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES2747-50UL MARK2 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology MARK2 rabbit pAb
ELK Biotechnology MARK2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | MARK2 rabbit pAb |
| Alternative Names | MARK2; EMK1; Serine/threonine-protein kinase MARK2; ELKL motif kinase 1; EMK-1; MAP/microtubule affinity-regulating kinase 2; PAR1 homolog; PAR1 homolog b; Par-1b; Par1b |
| Applications | WB; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MARK2 (AA range: 10–59) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 85 kD |
| GeneID (Human) | 2011 |
| Human Swiss-Prot No | Q7KZI7 |
| Species Reactivity | Human; Mouse; Rat; Monkey |
| Cellular Localization | Cell membrane; Peripheral membrane protein; Cytoplasm; Lateral cell membrane; Cytoplasm, cytoskeleton; Cell projection, dendrite. Phosphorylation at Thr-596 by PRKCZ/aPKC and subsequent interaction with 14-3-3 protein YWHAZ promotes relocation from the cell membrane to the cytoplasm. |
Background
Microtubule affinity regulating kinase 2 (MARK2) Homo sapiens.
This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [Provided by RefSeq, Jul 2009]
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