ELK Biotechnology KV3.2 rabbit pAb

제품명

KV3.2 rabbit pAb

제품 개요

본 항체는 인간 Potassium Channel Kv3.2b에서 유래한 합성 펩타이드를 면역원으로 제작된 토끼 폴리클로날 항체입니다. KCNC2 단백질을 인식하며, 다양한 응용 분야에서 사용 가능합니다.

대체 명칭

KCNC2; Potassium voltage-gated channel subfamily C member 2; Voltage-gated potassium channel Kv3.2

적용 분야 (Applications)

• Western Blot (WB)
• Immunohistochemistry (IHC)
• Immunofluorescence (IF)
• ELISA

권장 희석 배수 (Recommended Dilutions)

• WB: 1/500 – 1/2000
• IHC: 1/100 – 1/300
• ELISA: 1/10000
• 기타 응용은 미시험

면역원 (Immunogen)

Synthesized peptide derived from human Potassium Channel Kv3.2b (AA range: 589–638)

기술 사양

세포 내 위치 (Cellular Localization)

Cell membrane (multi-pass membrane protein), perikaryon, axon, dendrite, synapse (pre- and postsynaptic membranes), synaptosome, apical and basolateral cell membranes.
Colocalizes with parvalbumin in globus pallidus neurons, localizes in thalamocortical axons and synapses, and is detected throughout the neuropil. Also observed in starburst cell somata and proximal dendrites, colocalized with GABA in presynaptic terminals.

배경 (Background)

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and consists of four subfamilies. Based on sequence similarity, this gene belongs to the Shaw subfamily. The encoded protein is a delayed rectifier-type potassium channel that mediates voltage-dependent K⁺ ion permeability of excitable membranes. Multiple transcript variants encoding different isoforms have been identified for this gene (RefSeq, May 2012).