ELK Biotechnology IL-4Rα rabbit pAb
상품 옵션 정보 | ||||||
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카탈로그 번호 | 설명 | 상태 | 단위 | 가격 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
ES2617-100UL | ELK Biotechnology ES2617-100UL IL-4Rα rabbit pAb, 100UL pk | 재고문의 | pk | 469,000원 | 515,900원 | |
ES2617-50UL | ELK Biotechnology ES2617-50UL IL-4Rα rabbit pAb, 50UL pk | 재고문의 | pk | 320,000원 | 352,000원 |
다른 상품 둘러보기
Product name: | IL-4Rα rabbit pAb |
Alternative Names: | IL4R; IL4RA; 582J2.1; Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD antigen CD124 |
Applications: | WB;IF;ELISA |
Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
Immunogen: | The antiserum was produced against synthesized peptide derived from human IL-4R/CD124. AA range:463-512 |
Storage: | Rabbit |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 90kD |
GeneID(Human): | 3566 |
Human Swiss-Prot No: | P24394 |
Cellular localization: | Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted. |
Background: | This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012], |
Species Reactivity: | Human;Mouse |
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