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ELK Biotechnology HXK I rabbit pAb
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ELK Biotechnology HXK I rabbit pAb

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Hexokinase-1 단백질을 인식하는 rabbit polyclonal antibody로, WB, IHC, IF, ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. 미토콘드리아 외막 단백질 검출에 적합. -20°C에서 1년 보관 가능.

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ELK Biotechnology ES2587-100UL HXK I rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES2587-50UL HXK I rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology HXK I rabbit pAb

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HXK I rabbit pAb

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항목 내용
Alternative Names HK1; Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I
Applications WB; IHC; IF; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
Immunohistochemistry: 1/100 - 1/300
Immunofluorescence: 1/200 - 1/1000
ELISA: 1/20000
Not yet tested in other applications
Immunogen Synthesized peptide derived from human HXK1 (AA range: 31-80)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 109 kD
Gene ID (Human) 3098
Human Swiss-Prot No P19367
Species Reactivity Human; Mouse; Rat
Cellular Localization Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasm, cytosol. The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (Probable). Dissociates from the mitochondrial outer membrane following inhibition by N-acetyl-D-glucosamine, leading to relocation to the cytosol (PubMed:27374331).
Background Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. (RefSeq, Apr 2016)

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