ELK Biotechnology HSP40 rabbit pAb
HSP40 단백질에 특이적인 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 세포질 및 핵 내 위치 연구에 적합. 인간, 마우스, 랫트 반응성. 단백질 접힘 및 스트레스 반응 연구용.
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제품명
HSP40 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | DNAJB1; DNAJ1; HDJ1; HSPF1; DnaJ homolog subfamily B member 1; DnaJ protein homolog 1; Heat shock 40 kDa protein 1; HSP40; Heat shock protein 40; Human DnaJ protein 1; hDj-1 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HSP40 (AA range: 271–320) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 45 kDa |
| Gene ID (Human) | 3337 |
| Human Swiss-Prot No. | P25685 |
| Cellular Localization | Cytoplasm, Nucleus, Nucleolus. Translocates rapidly from the cytoplasm to the nucleus, especially to the nucleoli, upon heat shock. |
| Species Reactivity | Human, Mouse, Rat |
Background
This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the J-domain and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly.
The encoded protein acts as a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants.
(Provided by RefSeq, Sep 2015)
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