ELK Biotechnology HSL rabbit pAb
호르몬 민감성 리파아제(HSL)를 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA 등에 적합합니다. 인간, 생쥐, 랫트 반응성이 있으며 세포막 및 지질방울에서 발현되는 단백질 검출에 유용합니다. -20°C에서 1년 보관 가능합니다.
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제품명
HSL rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | LIPE; Hormone-sensitive lipase; HSL |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HSL (AA range: 518–567) |
| Species Reactivity | Human; Mouse; Rat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 120 kD |
| GeneID (Human) | 3991 |
| Human Swiss-Prot No | Q05469 |
| Storage | -20°C / 1 year |
| Host | Rabbit |
세포 내 위치
Cell membrane; Membrane, caveola; Cytoplasm, cytosol; Lipid droplet.
Found in high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation (PubMed:17026959).
Phosphorylation by AMPK reduces its translocation towards lipid droplets (By similarity).
단백질 배경
The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons.
The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production.
The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids.
[provided by RefSeq, Jul 2008]
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