ELK Biotechnology HoxD12 rabbit pAb
HOXD12 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA 등 다양한 응용 가능. 인간 및 마우스 시료에 반응하며, 핵에 위치한 HOXD12 단백질 검출에 적합. 고순도 IgG 형태로 -20°C에서 1년간 안정적 보관 가능.
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제품명
HoxD12 rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | HOXD12; HOX4H; Homeobox protein Hox-D12; Homeobox protein Hox-4H |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human HOXD12 (AA range: 191–240) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 28 kD |
| GeneID (Human) | 3238 |
| Human Swiss-Prot No | P35452 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Mouse |
Background
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters—HOXA, HOXB, HOXC, and HOXD—located on different chromosomes, consisting of 9 to 11 genes arranged in tandem.
This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5′ end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. (provided by RefSeq, Jul 2008)
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