ELK Biotechnology Histone H2A.X rabbit pAb
Histone H2A.X 단백질을 인식하는 rabbit polyclonal antibody로, WB, IHC, IF, CoIP, ELISA 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며, 고순도 IgG 형태로 -20°C에서 1년간 안정적으로 보관 가능합니다.
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ELK Biotechnology Histone H2A.X rabbit pAb
제품 개요
Histone H2A.X rabbit polyclonal antibody는 인간 Histone H2A.X 유래 합성 펩타이드(AA 94–143)에 대한 항혈청으로 제작되었습니다. 다양한 면역학적 실험(WB, IHC, IF, CoIP, ELISA)에 활용 가능하며, 인간, 마우스, 랫트 시료에서 반응합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | Histone H2A.X rabbit pAb |
| Alternative Names | H2AFX; H2AX; Histone H2A.x; H2a/x |
| Applications | WB; IHC; IF; CoIP; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 IP: 1/200–500 ELISA: 1/10000 Other applications: Not yet tested |
| Immunogen | Synthesized peptide derived from human Histone H2A.X (AA range: 94–143) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 19 kDa |
| Gene ID (Human) | 3014 |
| Human Swiss-Prot No. | P16104 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in chromatin compaction.
This gene encodes a replication-independent histone, a member of the histone H2A family, and generates two transcripts through the use of conserved stem-loop termination and polyA addition motifs.
(Provided by RefSeq, Oct 2015)
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