ELK Biotechnology Histone H1 rabbit pAb
Histone H1 rabbit polyclonal antibody로, 핵 내 히스톤 H1 단백질 검출에 적합합니다. WB, IHC, IF, ELISA 등 다양한 응용 가능. 인간 및 생쥐 시료 반응성. 고순도 IgG 형식으로 -20°C에서 1년 보관 가능.
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Histone H1 rabbit pAb
제품 개요
Histone H1 rabbit polyclonal antibody는 핵 내 히스톤 H1 단백질을 인식하는 항체로, 염색질 구조 연구 및 단백질 발현 분석에 활용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H1 rabbit pAb |
| Alternative Names | HIST1H1B; H1F5; Histone H1.5; Histone H1a; Histone H1b; Histone H1s-3; HIST1H1D; H1F3; Histone H1.3; Histone H1c; Histone H1s-2; HIST1H1E; H1F4; Histone H1.4; Histone H1b; Histone H1s-4 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Histone H1 (AA range: 1–50) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 31–28 kD |
| GeneID (Human) | 3009 / 3007 / 3008 |
| Human Swiss-Prot No | P16401 / P16402 / P10412 |
| Cellular Localization | Nucleus, Chromosome. According to PubMed:15911621, more commonly found in heterochromatin. According to PubMed:10997781, associates with actively transcribed chromatin and not heterochromatin. |
| Species Reactivity | Human; Mouse |
Background
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher-order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. (RefSeq, Aug 2015)
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