Thermo Fisher Scientific ENT1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ENT1 for IHC applications. Reacts with multiple species and purified by antigen affinity chromatography. Supplied in liquid form with PBS buffer and sodium azide. Suitable for research use only.
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- PA533030
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- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 10–12.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Bovine, Dog, Horse, Hamster, Human, Mouse, Non-human primate, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from C-terminus of human ENT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550491 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bat, Bovine, Hamster, Elephant, Panda, Horse, Rabbit (100%).
Target Information
The ENT1 gene is a member of the equilibrative nucleoside transporter family. It encodes a transmembrane glycoprotein that localizes to plasma and mitochondrial membranes and mediates cellular uptake of nucleosides from the surrounding medium. This equilibrative transporter is sensitive to inhibition by nitrobenzylthioinosine. Nucleoside transporters are essential for nucleotide synthesis in cells lacking de novo nucleoside synthesis pathways and for uptake of cytotoxic nucleosides used in cancer and antiviral chemotherapies. Multiple alternatively spliced variants encoding the same protein have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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