Thermo Fisher Scientific ANKRD13A Polyclonal Antibody
Human ANKRD13A 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin)에서 검증됨. 항원 친화 크로마토그래피로 정제된 액상 제품으로, 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ANKRD13A (amino acids 492–575). Recombinant protein control fragment: Product #RP-102937 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637926 |
Product Specific Information
Immunogen sequence:
IQQSLLESSR SQELSGPASN GGISQTNTYD AQYERAIQES LLTSTEGLCP SALSETSRFD NDLQLAMELS AKELEEWELR LQEE
Antigen sequence identity (orthologs):
- Mouse: 82%
- Rat: 79%
Target Information
ANKRD13A (also known as ANKRD13) is a 590 amino acid protein containing two ANK repeats and four UIM (ubiquitin-interacting motif) repeats. It localizes to the cell membrane and acts as a ubiquitin-binding protein that specifically recognizes and binds Lys-63-linked ubiquitin, but not Lys-48-linked ubiquitin. ANKRD13A positively regulates the internalization of ligand-activated EGFR by binding to the ubiquitinated EGFR at the cell membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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