Thermo Fisher Scientific DDX60L Polyclonal Antibody
Human DDX60L 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% 글리세롤) 용액 형태로 제공됩니다. 바이러스 면역 및 RNA 대사 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DDX60L. Recombinant protein control fragment (Product #RP-96766) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640488 |
Product Specific Information
Immunogen sequence:
QEPHLNLGDS IRRDYEDLWN VVSHLVKEFN LGKSFPLRTT RRHFLRQEKS VIQEISLEKM PSVGFIPMTS AVIDEFVGDM MKDL
Antigen sequence identity:
- Mouse: 51%
- Rat: 48%
Target Information
This gene encodes a member of the DExD/H-box helicase family of proteins, a subset of the superfamily 2 helicases. Members of this family share a conserved functional core composed of two RecA-like globular domains containing motifs for ATP binding, hydrolysis, nucleic acid binding, and RNA unwinding.
In addition to roles in RNA metabolism, these helicases are involved in antiviral immunity and act as cytosolic sensors of viral nucleic acids. The encoded protein has been shown to inhibit hepatitis C virus replication in response to interferon stimulation in cell culture. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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