Thermo Fisher Scientific PPP1R8 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:100

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human PPP1R8 (NP_612568.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PPP1R8,uniProtId:Q12972-1,ncbiNodeId:9606,antigenRange:1-209,antigenLength:351,antigenImageFileName:PA5-121027_PPP1R8_Q12972-1_Rabbit.svg,antigenImageFileNamePDP:PA5-121027_PPP1R8_Q12972-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

4.73 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914599

Product Specific Information

Positive test controls include: HL-60, PC-12, HeLa, HepG2, 293T, Mouse brain. The target is usually found in the following locations: Cytoplasm, Nucleus, Nucleus speckle.

Immunogen sequence: MGGEDDELKG LLGLPEEETE LDNLTEFNTA HNKRISTLTI EEGNLDIQRP KRKRKNSRVT FSEDDEIINP EDVDPSVGRF RNMVQTAVVP VKKKRVEGPG SLGLEESGSR RMQNFAFSGG LYGGLPPTHS EAGSQPHGIH GTALIGGLPM PYPNLAPDVD LTPVVPSAVN MNPAPNPAVY NPEAVNEPKK KKYAKEAWPG KKPTPSLLI

Target Information

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.