Thermo Fisher Scientific PPP1R8 Polyclonal Antibody
PPP1R8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 Affinity Chromatography 정제, 안정적 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific PPP1R8 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–209 of human PPP1R8 (NP_612568.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4.73 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914599 |
Product Specific Information
Positive test controls include HL-60, PC-12, HeLa, HepG2, 293T, Mouse brain.
Target localization: Cytoplasm, Nucleus, Nucleus speckle.
Immunogen Sequence:
MGGEDDELKG LLGLPEEETE LDNLTEFNTA HNKRISTLTI EEGNLDIQRP KRKRKNSRVT FSEDDEIINP EDVDPSVGRF RNMVQTAVVP VKKKRVEGPG SLGLEESGSR RMQNFAFSGG LYGGLPPTHS EAGSQPHGIH GTALIGGLPM PYPNLAPDVD LTPVVPSAVN MNPAPNPAVY NPEAVNEPKK KKYAKEAWPG KKPTPSLLI
Target Information
This gene encodes three isoforms through alternative splicing.
Two isoforms act as specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA.
The third isoform functions as a single-strand endoribonuclease similar to RNase E of E. coli, requiring magnesium to cleave A+U-rich regions of RNA.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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