Thermo Fisher Scientific NPPB Monoclonal Antibody (OTI8A9), TrueMAB
인간 NPPB 단백질(aa 27-102)을 면역원으로 제작된 Mouse monoclonal antibody. Western blot 및 Luminex에 적합하며, 동결건조 형태로 제공. PBS buffer(8% trehalose) 보존, -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Luminex (LUM) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 27–102 of human NPPB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene belongs to the natriuretic peptide family and encodes a secreted cardiac hormone.
The protein undergoes two cleavage events—one intracellularly and another after secretion into the bloodstream.
Its biological functions include:
- Natriuresis and diuresis
- Vasorelaxation
- Inhibition of renin and aldosterone secretion
- Regulation of cardiovascular homeostasis
Elevated levels in blood are indicative of heart failure.
Mutations in this gene are associated with postmenopausal osteoporosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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