Thermo Fisher Scientific ATF4 Polyclonal Antibody
Thermo Fisher Scientific의 ATF4 Polyclonal Antibody는 마우스 ATF4 단백질을 타깃으로 하는 친화 크로마토그래피 정제된 비결합 항체입니다. Western blot 및 IHC에 적합하며, 다양한 종에서 높은 상동성을 보입니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.2–1.0 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | Assay-dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of mouse ATF4 (aa 291–340) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | −20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688575 |
Product Specific Information
This target displays homology in the following species:
- Cow: 100%
- Dog: 93%
- Guinea Pig: 100%
- Horse: 79%
- Human: 93%
- Mouse: 100%
- Rat: 100%
- Sheep: 100%
Target Information
This gene encodes a transcription factor originally identified as a widely expressed mammalian DNA-binding protein that binds a tax-responsive enhancer element in the LTR of HTLV-1. It was also characterized as cAMP-response element binding protein 2 (CREB-2).
The encoded protein belongs to the AP-1 family of transcription factors, CREBs, and CREB-like proteins, sharing a leucine zipper region for protein-protein interactions and a basic DNA-binding domain.
Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 within a large inverted duplication region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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