Thermo Fisher Scientific IFN-Alpha Polyclonal Antibody
인간 IFN-Alpha를 인식하는 토끼 폴리클로날 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Protein A로 정제된 고순도 항체이며, 액상 형태로 -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human IFNA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins found exclusively in vertebrates. Interaction of IFN-alpha with its receptor activates multiple signaling pathways involved in innate immune responses against viral infections.
In humans, the IFN alpha gene is located on chromosome 9. Type I interferons include 14 alpha isoforms and single beta, omega, epsilon, and kappa isoforms. Homologous molecules exist in many species, including mammals, birds, reptiles, and fish.
IFN alpha is primarily produced by plasmacytoid dendritic cells and plays a key role in antiviral innate immunity and modulation of adaptive immune responses. Dysfunctions of IFN alpha are associated with diseases such as Hepatitis C and Hepatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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