Thermo Fisher Scientific CCNDBP1 Polyclonal Antibody
Rabbit polyclonal antibody against human CCNDBP1 for WB and ICC/IF applications. Antigen affinity purified, unconjugated, liquid form with 0.1 mg/mL concentration. Provides reliable detection and specificity in research use only assays.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CCNDBP1. Recombinant protein control fragment (Product #RP-104728) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662281 |
Product Specific Information
Immunogen sequence:
SPENNDLISYN SVWVACQQMP QIPRDNKAAA LLMLTKNVDF VKDAHEEMEQ AVEECDPYSG LLNDTEENNS DNHNHEDDVL GFPSNQD
Highest antigen sequence identity to the following orthologs:
- Mouse: 81%
- Rat: 76%
Target Information
This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene interacts with cyclin D and can reduce phosphorylation of the Rb gene product by cyclin D-dependent kinase, inhibiting E2F1-mediated transcription activity. It also interacts with helix-loop-helix protein E12 and is considered a negative regulator of liver-specific gene expression. Two alternatively spliced variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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