Thermo Fisher Scientific LZTR1 Polyclonal Antibody
LZTR1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 면역세포화학(ICC/IF)에 적합. 인간 및 생쥐 시료 반응성. 액상 형태로 제공되며, -20°C에서 보관. 연구용 전용 제품.
- 카탈로그번호
- PA5115529
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LZTR1 (Accession Q8N653), corresponding to amino acid residues P117–I167 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900165 |
Product Specific Information
This antibody detects endogenous levels of total LZTR1.
Target Information
LZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family. The encoded protein localizes exclusively to the Golgi network, where it may help stabilize the Golgi complex. Deletion of this gene may be associated with DiGeorge syndrome, a developmental defect involving the third and fourth pharyngeal pouches, leading to absence of thymus and parathyroid glands, congenital cardiac abnormalities, and facial dysmorphism. LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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