Thermo Fisher Scientific EWSR1 Monoclonal Antibody (OTI2G3)
EWSR1 단백질을 인식하는 마우스 모노클로날 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 고순도 친화 크로마토그래피로 정제되었으며, PBS/BSA/glycerol 버퍼에 보관됩니다. 인간 시료 반응성이 확인된 연구용 항체입니다.
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- TA813055
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 256–447 of human EWSR1 (NP_005234) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a multifunctional protein involved in gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various transcription factor genes result in chimeric proteins implicated in tumorigenesis, including Ewing sarcoma and other neuroectodermal tumors. Alternative splicing produces multiple transcript variants, and related pseudogenes have been identified on chromosomes 1 and 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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