Thermo Fisher Scientific EWSR1 Monoclonal Antibody (OTI2D9)
EWSR1 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 고순도 친화 크로마토그래피 정제, 1 mg/mL 액상 형태로 제공되며 안정적인 PBS/glycerol 저장 버퍼를 포함합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- TA813054
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 256–447 of human EWSR1 (NP_005234) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol, 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a multifunctional protein involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport.
The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain.
Chromosomal translocations between this gene and various genes encoding transcription factors result in chimeric proteins associated with tumorigenesis.
Mutations in this gene, specifically translocations, are known to cause Ewing sarcoma, neuroectodermal tumors, and other malignancies.
Alternative splicing results in multiple transcript variants, and related pseudogenes have been identified on chromosomes 1 and 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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