Thermo Fisher Scientific THAP1 Polyclonal Antibody
THAP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western Blot 및 Immunocytochemistry에 적합하며, 항원 친화 크로마토그래피로 정제된 고순도 제품입니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA577225
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- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: [참고 없음]
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
- Publications: [참고 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human THAP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720952 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
THAP1 is a DNA-binding transcription regulator that controls endothelial cell proliferation and G1/S cell-cycle progression. It binds specifically to the core DNA sequence 5'-[AT]NTNN[GT]GGCA[AGT]-3' and modulates expression of pRB-E2F cell-cycle target genes, including RRM1. It forms part of the THAP1/THAP3-HCFC1-OGT complex required for transcriptional regulation of RRM1 and may also promote apoptosis under serum-withdrawal or TNF-induced conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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