Thermo Fisher Scientific Caspase 1 p10 (Cleaved Ala317) Polyclonal Antibody
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PA539882 | - | Thermo Fisher Scientific PA539882 Caspase 1 p10 (Cleaved Ala317) Polyclonal Antibody 100 ug pk | 재고문의 | pk | 0원 | - | 0원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:3,000
View 1 publication 1 publication
Product Specifications
Published species
Rat
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide derived from human CASP1
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2556431
Target Information
Caspase-1 (CASP1) is a thiol protease that cleaves IL-1 beta between Asp and Ala. This cleavage causes the release of the mature cytokine which is involved in a variety of inflammatory processes. CASP1 is important for defense against pathogen. It cleaves and activates sterol regulatory element binding proteins (SREBPs). CASP1 also promotes apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, CASP1 controls antiviral immunity through the cleavage of CGAS and renders it inactive.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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