Thermo Fisher Scientific MASP1 (Cleaved Arg448) Polyclonal Antibody
MASP1 단백질의 절단된 Arg448 부위를 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인체 MASP1 유래 합성 펩타이드로 면역화되었으며, 비결합형 액상 형태로 제공됩니다. 보관은 -20°C에서, 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific MASP1 (Cleaved Arg448) Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from human MASP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556430 |
Target Information
This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of the lectin pathway, including mannose-binding lectin and ficolins.
This protein is not directly involved in complement activation but may act as an amplifier by cleaving complement C2 or activating another complement serine protease, MASP-2. It can also cleave fibrinogen and factor XIII, suggesting a potential role in coagulation. A splice variant lacking the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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