Thermo Fisher Scientific JMJD2B Polyclonal Antibody

Thermo Fisher Scientific JMJD2B Polyclonal Antibody

Applications

• Western Blot (WB)
  Tested Dilution: 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: SASRASLKAK LLRRSHRKRS QPKKPKPEDP KFPGEGTAGA ALLEEAGGSV
• Storage guidance:
  • Short term: Store at 2–8°C up to 1 week
  • Long term: Store at -20°C in small aliquots to prevent freeze-thaw cycles
• Predicted homology:
  Cow: 92%; Dog: 93%; Guinea Pig: 83%; Horse: 93%; Human: 100%; Mouse: 82%; Pig: 93%; Rat: 100%

Target Information

Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a role in histone code.
Does not demethylate histone H3 Lys-4, H3 Lys-27, H3 Lys-36 nor H4 Lys-20.
Only able to demethylate trimethylated H3 Lys-9, with weaker activity than KDM4A, KDM4C, and KDM4D.
Demethylation of Lys residue generates formaldehyde and succinate. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.