Takara Pyrophosphatase, HQ

Pyrophosphatase (inorganic), HQ (High-Quality) is a high-quality enzyme that catalyzes the hydrolysis of inorganic pyrophosphate (PPi) to form orthophosphates. Pyrophosphatase (inorganic), HQ enhances RNA or DNA synthesis by degrading the byproduct, PPi generated in the reaction.

A GMP grade T7 RNA Polymerase is available upon request. Please contact us (Inside_Sales@takarabio.com) for more information.

Do you want to explore OEM options? Contact OEM Services & Support (oem@takarabio.com).

Pyrophosphatase (inorganic), HQ (High-Quality) is a high-quality enzyme that catalyzes the hydrolysis of inorganic pyrophosphate (PPi) to form orthophosphates. Pyrophosphatase (inorganic), HQ enhances RNA or DNA synthesis by degrading the byproduct, PPi generated in the reaction.

Pyrophosphatase (inorganic), HQ is comparable to RUO grade Pyrophosphatase (inorganic) (Cat # 2450A/B), however, it has stricter quality standards than the RUO grade (see the table below) with a high volume (1 ml/tube) for your scale-up process.

Pyrophosphatase (inorganic), HQ is intended for use in the preparation of active pharmaceutical ingredients (APIs) for non-clinical trials, as well as for the process development of drug manufacturing under good manufacturing practice (GMP) regulation. Its similarity to GMP grade enzymes makes it a smooth transition from non-GMP to GMP grade RNA manufacturing while maintaining relevant safety and efficacy standards. In addition to its use in drug manufacturing, pyrophosphatase (inorganic), HQ can also be used for basic research in the field of therapeutics.

It is free from human- or animal-derived materials, as well as β-lactam compounds in the final formulation. This makes it suitable for use in applications where there is a risk of immunogenic reactions.

A GMP-grade T7 RNA Polymerase is available upon request. Please contact us (Inside_Sales@takarabio.com) for more information.

Do you want to explore OEM options? Contact OEM Services & Support (oem@takarabio.com).

More Less

Overview

This kit can be used for synthesis of RNA to be used in many applications:

1. RNA yield enhancement in in vitro transcription reaction
2. Promotion of DNA amplification reaction

More Information

Additional product information

Please see the product`s Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Product Components List to determine kit components. Certificates of Analysis and Product Components Lists are located under the Documents tab.