Thermo Fisher Scientific ACAT2 Monoclonal Antibody (OTI1B7), TrueMAB
ACAT2 단백질을 인식하는 Mouse IgG2b 단클론 항체로, Western blot, IHC, ICC/IF, Flow cytometry 등에 사용 가능. 인간, 개, 쥐 시료에 반응하며, 고순도 친화성 크로마토그래피 정제. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B7 |
| Immunogen | Full length human recombinant protein of human ACAT2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.57 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene represents a member of the frizzled gene family, which encodes 7-transmembrane domain proteins that are receptors for Wnt signaling proteins.
The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif.
This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting oncogenic transformation, cell proliferation, and inhibition of apoptosis.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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