Thermo Fisher Scientific GRP94 Polyclonal Antibody
다중 응용 분야(WB, IHC, ICC, Flow, ELISA)에 적합한 GRP94 폴리클로날 항체. 인간, 마우스, 랫트 반응성. Rabbit IgG 기반, Protein A 정제, 액상 형태. 연구용으로 단백질 처리 및 면역 반응 연구에 활용 가능.
- 카탈로그번호
- BS-0194R
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GRP94 Polyclonal Antibody
Thermo Fisher Scientific GRP94 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human GRP94, amino acids 554–650 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
GRP94 is an 803 amino acid protein belonging to the heat shock protein 90 family. It functions as a molecular chaperone involved in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulate CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate and acquired immunity, dendritic cell maturation and chemotaxis, antibody production, and cross-priming. GRP94 is a potential marker in breast cancer and acts as a peptide acceptor in the endoplasmic reticulum, aiding peptide loading of MHC class I molecules. Expression of GRP94 suppresses A23187-induced apoptosis and stabilizes calcium homeostasis. GRP94 is expressed in melanoma, liver metastases of colon carcinoma, and human gastric carcinoma BGC-823 cells.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.